920757-89-7Relevant academic research and scientific papers
Synthesis of model BC bicycles of taxol using C10-C11 ring-closing metathesis strategy
Schiltz, Stéphanie,Ma, Cong,Ricard, Louis,Prunet, Jo?lle
, p. 5438 - 5443 (2007/10/03)
Model BC ring-systems of taxol 23b and 28b, which lack an oxygenated substituent at C7, have been efficiently synthesized. The key step is a ring-closing metathesis (RCM) to form the 8-membered B ring between C10 and C11. Comparison of the metathesis reac
