920757-92-2Relevant academic research and scientific papers
Ring-closing metathesis in the synthesis of BC ring-systems of taxol
Ma, Cong,Schiltz, Stéphanie,Le Goff, Xavier F.,Prunet, Jo?lle
experimental part, p. 7314 - 7323 (2009/08/07)
BC ring-systems of taxol with different or no protecting group for the C1,C2-diol moiety have been efficiently synthesized. The eight-membered B ring is formed by a ring-closing metathesis reaction (RCM) between the C10 and C11 carbon atoms. The influence
Synthesis of model BC bicycles of taxol using C10-C11 ring-closing metathesis strategy
Schiltz, Stéphanie,Ma, Cong,Ricard, Louis,Prunet, Jo?lle
, p. 5438 - 5443 (2007/10/03)
Model BC ring-systems of taxol 23b and 28b, which lack an oxygenated substituent at C7, have been efficiently synthesized. The key step is a ring-closing metathesis (RCM) to form the 8-membered B ring between C10 and C11. Comparison of the metathesis reac
