920759-17-7

Basic information

• Product Name: C₂₈H₂₇BrFNO₅S
• CAS NO: 920759-17-7
• Molecular Weight: 588.494
• Mol File: 920759-17-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₇BrFNO₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₇BrFNO₅S(920759-17-7)
• EPA Substance Registry System: C₂₈H₂₇BrFNO₅S(920759-17-7)

Safety Data

• Hazardous Substances Data: 920759-17-7(Hazardous Substances Data)

Upstream product

• 773100-76-8 5-(bromomethyl)-2-fluorobenzoic acid 
• 2731-16-0 deacetylthiocolchicine 

Relevant articles and documents

Design, synthesis and identification of novel colchicine-derived immunosuppressant

Synthesis and biological evaluation of various colchicine analogues through the mixed-lymphocyte reaction (MLR), lymphoproliferation, and inhibitory effects on the inflammatory genes are described. In addition, a new series of immunosuppressive agents developed on the structural basis of colchicine, as well as their structure-activity relationships is reported. The most potent analogue 20a exhibited an excellent immunosuppressive activity on in vivo skin-allograft model, which is comparable to that of cyclosporin A.