92077-78-6 Usage
Description
Cilazapril is a potent and long-lasting angiotensin-converting enzyme (ACE) inhibitor, used in the management of mild to moderate hypertension. It is a prodrug that is de-esterified to its active diacid metabolite cilazaprilat upon oral administration. Cilazapril is characterized by its white or almost white crystalline powder form and exhibits more potency and longer duration of action compared to other ACE inhibitors like enalapril and captopril.
Uses
Used in Pharmaceutical Industry:
Cilazapril is used as an antihypertensive agent for the treatment of mild to moderate hypertension. It functions by inhibiting the angiotensin-converting enzyme, which in turn reduces the production of angiotensin II, a potent vasoconstrictor. This leads to vasodilation, decreased peripheral resistance, and ultimately, a reduction in blood pressure.
The use of Cilazapril in the pharmaceutical industry is primarily for its therapeutic effects in managing hypertension, providing a more potent and longer-lasting alternative to other ACE inhibitors. Its chemical properties and mode of action make it a valuable component in the development of antihypertensive medications.
Check Digit Verification of cas no
The CAS Registry Mumber 92077-78-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,0,7 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 92077-78:
(7*9)+(6*2)+(5*0)+(4*7)+(3*7)+(2*7)+(1*8)=146
146 % 10 = 6
So 92077-78-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H31N3O5.H2O/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26;/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28);1H2/t17-,18-,19-;/m0./s1