920979-04-0

Basic information

• Product Name: 3-Amino-2-iodo-6-(trifluoromethyl)-pyridine
• Synonyms: 3-Amino-2-iodo-6-(trifluoromethyl)-pyridine;3-Amino-6-iodo-2-trifluoromethylpyridine;5-Amino-6-iodo-2-(trifluoromethyl)pyridine
• CAS NO: 920979-04-0
• Molecular Formula: C₆H₄F₃IN₂
• Molecular Weight: 288.01
• Mol File: 920979-04-0.mol

Chemical Properties

• Boiling Point: 233.1°C at 760 mmHg
• Flash Point: 94.8°C
• Appearance: /
• Density: 1.892g/cm³
• Vapor Pressure: 0.0867mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-Amino-2-iodo-6-(trifluoromethyl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-2-iodo-6-(trifluoromethyl)-pyridine(920979-04-0)
• EPA Substance Registry System: 3-Amino-2-iodo-6-(trifluoromethyl)-pyridine(920979-04-0)

Safety Data

• Hazardous Substances Data: 920979-04-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Amino-2-iodo-6-(trifluoromethyl)-pyridine is used as a building block in organic synthesis for the creation of various heterocyclic compounds and functional materials. Its unique structural features and reactivity make it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-Amino-2-iodo-6-(trifluoromethyl)-pyridine is used as a key intermediate in drug design and discovery. Its trifluoromethyl group is particularly advantageous, as fluorine substitutions are known to enhance the stability, solubility, and overall pharmacological profile of drug candidates, potentially leading to improved therapeutic efficacy and safety.
Used in Drug Design and Discovery:
3-Amino-2-iodo-6-(trifluoromethyl)-pyridine is employed as a structural moiety in drug design and discovery, where its unique combination of functional groups can be leveraged to create novel bioactive molecules with enhanced properties. The presence of the trifluoromethyl group can significantly impact the physicochemical and pharmacological characteristics of the resulting compounds, making it a promising candidate for the development of new therapeutic agents.

InChI:InChI=1/C6H5FIN/c1-4-2-3-5(8)6(7)9-4/h2-3H,1H3

Upstream product

• 106877-33-2 6-(trifluoromethyl)pyridin-3-amine 

Downstream Products

• 920979-05-1 (5-trifluoromethyl)pyrrolo[3,2-b]pyridine-2-carboxylic acid 
• 1314841-37-6 5-[[1-[[3-(1,1-dimethylethyl)phenyl]sulfonyl]-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]methyl]-thiophene-2-carboxylic acid 
• 1314841-35-4 [1-(3-(1,1-dimethylethyl)phenylsulfonyl)-5-trifluoromethyl-1H-pyrrolo[3,2-b]pyridin-2-yl]methanol 
• 1314841-36-5 2-bromomethyl-1-(3-(1,1-dimethylethyl)phenylsulfonyl)-5-trifluoro-methyl-1H-pyrrolo[3,2-b]pyridine 
• 1314186-71-4 3-(1,1-dimethylethyl)-N-(2-iodo-6-trifluoromethylpyridin-3-yl)benzenesulfonamide 
• 1068971-33-4 2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (3-ethyl-5-trifluoromethyl-pyrrolo[3,2-b]pyridin-1-yl)-amide 
• 1314841-92-3 2-bromomethyl-1-(3-(1,1-dimethylethyl)phenylsulfonyl)-3-methyl-5-trifluoromethyl-1H-pyrrolo[3,2-b]pyridine 
• 1314841-91-2 4-[[1-[[3-(1,1-dimethylethyl)phenyl]sulfonyl]-3-methyl-5-(trifluoro-methyl)-1H-pyrrolo[3,2-b]pyridin-2-yl]methyl]benzoic acid 
• 1314841-90-1 1-(3-(1,1-dimethylethyl)phenylsulfonyl)-2,3-dimethyl-5-trifluoro-methyl-1H-pyrrolo[3,2-b]pyridine 
• 1314841-50-3 2-[1-(3-(1,1-dimethylethyl)phenylsulfonyl)-5-trifluoromethyl-1H-pyrrolo[3,2-b]pyridin-2-yl]thioacetamide 
• 1314841-49-0 [1-(3-(1,1-dimethylethyl)phenylsulfonyl)-5-trifluoromethyl-1H-pyrrolo[3,2-b]pyridin-2-yl]acetonitrile 

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