921145-26-8

Basic information

• Product Name: N-(1,3-Thiazol-5-ylmethyl)propan-2-amine dihydrochloride
• Synonyms: N-(1,3-Thiazol-5-ylmethyl)propan-2-amine dihydrochloride;N-(1,3-thiazol-5-ylmethyl)propan-2-amine
• CAS NO: 921145-26-8
• Molecular Formula: C7H14Cl2N2S
• Molecular Weight: 229.17046
• Mol File: 921145-26-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(1,3-Thiazol-5-ylmethyl)propan-2-amine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,3-Thiazol-5-ylmethyl)propan-2-amine dihydrochloride(921145-26-8)
• EPA Substance Registry System: N-(1,3-Thiazol-5-ylmethyl)propan-2-amine dihydrochloride(921145-26-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 921145-26-8(Hazardous Substances Data)

Downstream Products

• 1424330-34-6 C₁₉H₂₀Cl₂N₄O₂S 

Relevant articles and documents

Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries

Optimization of a high-throughput screening hit led to the discovery of a new series of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as highly potent agonists of TGR5. This novel chemotype was rapidly developed through iterative combinatorial library synthesis. It was determined that in vitro agonist potency correlated with functional activity data from human peripheral blood monocytes.