921202-72-4

Upstream product

• 634181-81-0 (2R,4R)-4-(benzyloxy)-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-3,3-difluoro-2-hydroxybutyl benzoate 
• 921202-48-4 (2R,5R)-4-O-benzyl-1-O-benzoyl-3,3-difluoro-5,6-O-isopropylidenehexane-1,2,4,5,6-pentol 
• 921202-63-3 Benzoic acid (S)-2-acetylsulfanyl-4-benzyloxy-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3,3-difluoro-butyl ester 
• 921202-67-7 1-O-acetyl-2-O-benzyl-5-O-benzoyl-3-deoxy-3,3-difluoro-4-thio-L-xylofuranose 
• 921202-55-3 (2S,4R,5R)-4-O-benzyl-1-O-benzoyl-3,3-difluoro-5,6-O,O-isopropylidenehex-2-yl ethanethioate 

Downstream Products

• 921202-81-5 1-(2,5-di-O-benzoyl-3-deoxy-3,3-difluoro-4-thio-β-L-xylofuranosyl)uracil 
• 921202-86-0 1-(2,5-di-O-benzoyl-3-deoxy-3,3-difluoro-4-thio-β-L-xylofuranosyl)thymine 
• 921202-91-7 N⁴-benzoyl-1-(2,5-di-O-benzoyl-3-deoxy-3,3-difluoro-4-thio-β-L-xylofuranosyl)cytosine 

Relevant academic research and scientific papers

Synthesis of L-β-3′-deoxy-3′,3′-difluoro-4′- thionucleosides

(Chemical Equation Presented) An efficient route to L-β-3′- deoxy-3′,3′-difluoro-4′-thionucleosides, thio-containing analogues of highly bioactive gemcitabine, is described. Our synthesis highlighted the installation of the thioacetyl group in high effici