92133-91-0Relevant academic research and scientific papers
Aminopyrazoles. V . Structure Assignment of 1H-Pyrazol-3- and 5-amines by Means of the 1H NMR δ(4-H)-Values of Their exo-N-Toluenesulfonyl Derivatives
Ege, Guenter,Franz, Hermann
, p. 689 - 695 (2007/10/02)
From the extent of the low field chemical shift of 4-H caused by exo-N-tosylation of 1-substituted 1H-pyrazolamines it is possible to distinguish between the 3- and 5-amino-isomers.The pyrazole substituent increment system of Tensmeyer and Ainsworth has been extended to 3- and 5-amino, 3- and 5-tosylamino, 1-benzyl and 1-tosyl substituents.By comparison of δ(4-H) values, calculated with the aid of these increments, with measured δ(4-H) values, a differentiation between 3- and 5-tosylaminopyrazoles but not between 3- and 5-aminopyrazoles can be made.
