92144-23-5 Usage
Uses
Used in Pharmaceutical Development:
2,4-diamino-N-[2-(diethylamino)ethyl]-N-methylquinazoline-6-sulfonamide is used as a potential pharmaceutical agent for its possible antibacterial properties, given the known activities of sulfonamides. The presence of the quinazoline core, which is often found in compounds with antitumor and antifungal activities, suggests that 2,4-diamino-N-[2-(diethylamino)ethyl]-N-methylquinazoline-6-sulfonamide may also have potential in these areas.
Used in Antibacterial Applications:
In the field of infectious diseases, 2,4-diamino-N-[2-(diethylamino)ethyl]-N-methylquinazoline-6-sulfonamide is considered for its potential use as an antibacterial agent, leveraging the traditional benefits of sulfonamide compounds in treating bacterial infections.
Used in Antitumor and Antifungal Research:
2,4-diamino-N-[2-(diethylamino)ethyl]-N-methylquinazoline-6-sulfonamide is used as a subject of research in oncology and mycology due to the quinazoline core's known associations with antitumor and antifungal activities. 2,4-diamino-N-[2-(diethylamino)ethyl]-N-methylquinazoline-6-sulfonamide's structure may offer new avenues for the development of treatments for cancer and fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 92144-23-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,1,4 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 92144-23:
(7*9)+(6*2)+(5*1)+(4*4)+(3*4)+(2*2)+(1*3)=115
115 % 10 = 5
So 92144-23-5 is a valid CAS Registry Number.
92144-23-5Relevant academic research and scientific papers
Elslager,Colbry,Davoll,Hutt,Johnson,Werbel
, p. 1740 - 1743 (1984)
The synthesis and antimalarial activity of a series of 2,4-diamino-6-quinazolinesulfonamides is described. Chlorosulfonation of 2,4-quinazolinediamine affords the 6-sulfonyl chloride, which upon treatment with the appropriate amine produces the desired products. Alternatively the sulfonyl chloride could be introduced by diazotization of the corresponding amine followed by treatment with SO2 in the presence of CuCl2. Although substantial antimalarial activity was demonstrated for several members of this class, studies were discontinued in light of the potency of related series.
