921440-72-4Relevant academic research and scientific papers
Dearylation with aromatization on cyclocondensation of 4-(dimethyl-amino) benzaldehyde, 2-phenacylaza-heterocycles, and 1,3-[N,C]dinucleophiles
Dzvinchuk
experimental part, p. 85 - 92 (2009/07/09)
Three-component cyclocondensation involving p-(dimethylamino)benzaldehyde, 2-phenacylazahetero-cycle, and a 1,3-[N,C]-nucleophile (3,5-dimethoxyaniline, 6-amino-1,3-dimethylpyrimidine-2,4-dione, 1-amino-3-methyl-5-phenylpyrazole) in boiling acetic acid is
p-(dimethylamino)benzaldehyde modification of the Hantzsch reaction: Synthesis of 3-(1H-benzimidazol-2-yl)-5,7-dimethoxyquinolines
Dzvinchuk,Chernega,Lozinskii
, p. 1519 - 1524 (2008/09/20)
A three component cyclocondensation of p-(dimethylamino)benzaldehyde with 3,5-dimethoxyaniline and 2-phenacyl-1H-benzimidazoles gives previously unknown 2-aryl-3-(1H-benzimidazol-2-yl)-5,7-dimethoxyquinolines. The Hanztsch type reaction occurs in refluxing acetic acid and is accompanied by aromatization of the 1,4-dihydroquinolines formed through loss of N,N-dimethylaniline.
