92146-38-8 Usage
Uses
Used in Pharmaceutical Research:
[(5,7-dichloroquinolin-8-yl)oxy]acetic acid is utilized as a building block in the development of pharmaceutical drugs, specifically targeting its potential antitumor and antimalarial properties. The quinoline structure, which is common in many biologically active compounds, has shown promise in combating cancer cells and malaria parasites, making it a valuable asset in the creation of novel therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, [(5,7-dichloroquinolin-8-yl)oxy]acetic acid serves as a key precursor for the synthesis of various organic compounds. Its unique structure allows for the development of new molecules with potential applications in different industries, such as agrochemicals, dyes, and materials science.
Used in Anticancer Applications:
[(5,7-dichloroquinolin-8-yl)oxy]acetic acid is explored for its potential as an anticancer agent, leveraging its quinoline-based structure to target and inhibit the growth of cancer cells. Further research and development in this area could lead to the creation of new drugs that are effective against various types of cancer.
Used in Antimalarial Applications:
[(5,7-dichloroquinolin-8-yl)oxy]acetic acid's quinoline structure also makes it a candidate for antimalarial drug development. Malaria remains a significant global health concern, and the development of new, effective treatments is crucial. [(5,7-dichloroquinolin-8-yl)oxy]acetic acid's potential in this area could contribute to the fight against this deadly disease.
Check Digit Verification of cas no
The CAS Registry Mumber 92146-38-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,1,4 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 92146-38:
(7*9)+(6*2)+(5*1)+(4*4)+(3*6)+(2*3)+(1*8)=128
128 % 10 = 8
So 92146-38-8 is a valid CAS Registry Number.
92146-38-8Relevant academic research and scientific papers
Romano, Elida,Castillo, María V.,Pergomet, Jorgelina L.,Zinczuk, Juan,Brandán, Silvia A.
, p. 149 - 155 (2012)
We have prepared the (5,7-dichloro-quinolin-8-yloxy) acetic acid and characterized it by infrared and Raman spectroscopies in the solid phase and by nuclear magnetic resonance (NMR) spectroscopy in a CDCl3 solution. The density functional theory (DFT) together with the 6-31G and 6-311++G basis sets were used to study its structure and vibrational properties. Two stable conformations of the compound were theoretically determined in the gas phase and probably these conformations are present in the solid phase. The harmonic vibrational wavenumbers for the optimized geometries were calculated at the same theory levels. For a complete assignment of all the observed bands in the vibrational spectra the DFT calculations were combined with Pulay's scaled quantum mechanical force field (SQMFF) methodology in order to fit the theoretical wavenumber values to the experimental ones. The force constants for the (5,7-dichloro-quinolin-8-yloxy) acetic acid were calculated and compared with those obtained for the (5-chloro-quinolin-8-yloxy) acetic acid and 2-(quinolin-8-yloxy)-acetic acid compounds. Furthermore, the characteristics of the electronic delocalization, the topological properties of the electronic charge density together with the highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) energy gaps were studied.
