92161-30-3Relevant academic research and scientific papers
Benzoxaborole-1-alcohol compound and preparation method and application thereof
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Paragraph 0143-0144; 0148-0150, (2020/06/24)
The invention belongs to the field of bactericides, and particularly relates to a benzoxaborole-1-alcohol compound and a preparation method and application thereof. The benzoxaborole-1-alcohol compound has good bactericidal activity, can effectively control tomato early blight, wheat scab, rice sheath blight disease, strawberry gray mold, apple blotch, cucumber anthracnose and other crop diseases,can produce excellent antibacterial effects at low concentration, and shows good selectivity. The compound is used as a leucyl-tRNA synthetase inhibitor, the evolution difference of aminoacyl-tRNA synthetase of germs and eukaryotes is utilized, and the compound has very high safety to non-target organisms while killing the germs and can be used as a bactericide in agriculture.
BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS
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Page/Page column 149; 150, (2010/04/30)
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
Discovery of novel benzoxaborole-based potent antitrypanosomal agents
Ding, Dazhong,Zhao, Yaxue,Meng, Qingqing,Xie, Dongsheng,Nare, Bakela,Chen, Daitao,Bacchi, Cyrus J.,Yarlett, Nigel,Zhang, Yong-Kang,Hernandez, Vincent,Xia, Yi,Freund, Yvonne,Abdulla, Maha,Ang, Kean-Hooi,Ratnam, Joseline,McKerrow, James H.,Jacobs, Robert T.,Zhou, Huchen,Plattner, Jacob J.
scheme or table, p. 165 - 169 (2010/10/21)
We report the discovery of benzoxaborole antitrypanosomal agents and their structure?activity relationships on central linkage groups and different substitution patterns in the sulfur-linked series. The compounds showed in vitro growth inhibition IC5
