921755-43-3 Usage
Structure
1-Azabicyclo[2.2.1]heptane-2-carboxylic acid, ethyl ester, (1R,2S,4R)-rel-
Appearance
White solid at room temperature
Solubility
Soluble in organic solvents
Uses
Building block in the synthesis of pharmaceuticals and agrochemicals, intermediate in the production of various drugs, chiral building block in the synthesis of complex organic molecules
Importance
Potential to form biologically active compounds, used in drug development and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 921755-43-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,1,7,5 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 921755-43:
(8*9)+(7*2)+(6*1)+(5*7)+(4*5)+(3*5)+(2*4)+(1*3)=173
173 % 10 = 3
So 921755-43-3 is a valid CAS Registry Number.
921755-43-3Relevant articles and documents
Synthesis of bicyclic tertiary α-amino acids
Strachan, Jon-Paul,Whitaker, Regina C.,Miller, Craig H.,Bhatti, Balwinder S.
, p. 9909 - 9911 (2007/10/03)
Novel bicyclic α-amino acids, exo and endo-1-azabicyclo-[2.2.1] heptane-2-carboxylic acid, 1-azabicyclo[2.2.1]heptane-7-carboxylic acid, and 1-azabicyclo[3.2.2]nonane-2-carboxylic acid have been readily synthesized for the generation of neuronal nicotinic receptor ligands. Alkylation of glycine-derived Schiff bases or nitroacetates with cyclic ether electrophiles, followed by acid-induced ring opening and cyclization in NH4OH, allowed for the preparation of substantial quantities of the three tertiary bicyclic α-amino acids.
N-ARYL DIAZASPIRACYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF
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Page 71, (2008/06/13)
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