921771-33-7

Upstream product

• 921771-32-6 3-[2-(2-benzyloxycarbonylamino-4-tert-butoxycarbonyl-butyrylamino)-6-tert-butoxycarbonylamino-hexanoylamino]-4,5-dihydroxy-pentanoic acid ethyl ester 
• 21900-37-8 2,6-dimethylbenzoyl chloride 
• 104274-42-2 (S)-3-Amino-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid ethyl ester 
• 921771-31-5 4-benzyloxycarbonylamino-4-{5-tert-butoxycarbonylamino-1-[1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-ethoxycarbonyl-ethylcarbamoyl]-pentylcarbamoyl}-butyric acid tert-butyl ester 
• 921771-29-1 3-(2-benzyloxycarbonylamino-6-tert-butoxycarbonylamino-hexanoylamino)-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid ethyl ester 
• 921771-30-4 3-(2-amino-6-tert-butoxycarbonylamino-hexanoylamino)-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid ethyl ester 
• 165133-39-1 3-benzylamino-3-(2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid ethyl ester 
• 917877-01-1 R-3-(2,2-dimethyl[1,3]dioxolan-4-yl)-acrylic acid ethyl ester 

Downstream Products

• 921771-35-9 2,6-dimethyl-benzoic acid 3-[6-amino-2-(2-benzyloxycarbonylamino-4-carboxy-butyrylamino)-hexanoylamino]-4-carboxy-2-oxo-butyl ester 
• 921771-34-8 2,6-dimethyl-benzoic acid 3-[2-(2-benzyloxycarbonylamino-4-tert-butoxycarbonyl-butyrylamino)-6-tert-butoxycarbonylamino-hexanoylamino]-4-ethoxycarbonyl-2-oxo-butyl ester 

Relevant academic research and scientific papers

Synthesis of novel caspase inhibitors for characterization of the active caspase proteome in vitro and in vivo

Caspases are cysteine proteases that are essential for cytokine maturation and apoptosis. To facilitate the dissection of caspase function in vitro and in vivo, we have synthesized irreversible caspase inhibitors with biotin attached via linker arms of va