921852-38-2Relevant academic research and scientific papers
Pyridopyrimidine protein tyrosine phosphatase inhibitors
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Page/Page column 36, (2008/06/13)
The present invention comprises pyridopyrimidinediamine compounds of the general formula I: The compounds of the present invention are potent inhibitors of PTP1B. Accordingly, the invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.
