92188-06-2

Basic information

• Product Name: 1-methyl-3-(3-methylbenzyl)thiourea
• CAS NO: 92188-06-2
• Molecular Weight: 194.301
• Mol File: 92188-06-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-3-(3-methylbenzyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-3-(3-methylbenzyl)thiourea(92188-06-2)
• EPA Substance Registry System: 1-methyl-3-(3-methylbenzyl)thiourea(92188-06-2)

Safety Data

• Hazardous Substances Data: 92188-06-2(Hazardous Substances Data)

Upstream product

• 100-81-2 3-methyl-benzenemethanamine 
• 556-61-6 methyl thioisocyanate 

Relevant articles and documents

N-methylthioureas as new agonists of retinoic acid receptor-related orphan receptor

Thirty two thiourea derivatives were prepared and their agonistic activities on the retinoic acid receptor-related orphan receptor α (RORα) were evaluated. The replacement of the 3-allyl-2-imino-thiazolidin- 4-one moiety of the lead compound CGP52608 (1) with various functional group substituted aromatic rings, improved the agonistic activity of RORα. Among the prepared derivatives, 1-methyl-3-(4-phenoxy-benzyl)-thiourea (32) showed 2.6-fold higher agonistic activity than CGP52608 in the RORα-activation assay.