921929-76-2Relevant articles and documents
6′-Chloro-7- or 9-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-7H- or 9H-purines and their corresponding sulfones as a new family of cytotoxic drugs
Nú?ez, María C.,Rodríguez-Serrano, Fernando,Marchal, Juan A.,Caba, Octavio,Aránega, Antonia,Gallo, Miguel A.,Espinosa, Antonio,Campos, Joaquín M.
, p. 183 - 190 (2007)
A series of 1-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)pyrimidine derivatives were synthesized and two of them (8 and 9) showed a modest antiproliferative activity against the MCF-7 breast cancer cell line. We then decided to change the pyrimidine base for