92207-69-7Relevant articles and documents
MODIFIED AZA-CLAISEN REARRANGEMENT: GENERATION AND ISOMERIZATION OF ALLYL ENAMMONIUM SALTS
Gilbert, John C.,Senaratne, K. P. A.
, p. 2303 - 2306 (2007/10/02)
Base-promoted reaction of ketones and diethyl (diazomethyl)phosphonate in the presence of allylic amines affords allylic enamines in good yields.These enamines undergo -sigmatropic rearrangement upon alkylation and heating at 80 deg C to iminium salts which can be hydrolyzed to aldehydes.The procedure allows generation of quaternary carbon centers under mild reaction conditions.