Welcome to LookChem.com Sign In|Join Free
  • or
3-NITRO-2H-CHROMENE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

92210-53-2

Post Buying Request

92210-53-2 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

92210-53-2 Usage

Synthesis Reference(s)

Synthesis, p. 348, 1984 DOI: 10.1055/s-1984-30841

Check Digit Verification of cas no

The CAS Registry Mumber 92210-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,2,1 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 92210-53:
(7*9)+(6*2)+(5*2)+(4*1)+(3*0)+(2*5)+(1*3)=102
102 % 10 = 2
So 92210-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO3/c11-10(12)8-5-7-3-1-2-4-9(7)13-6-8/h1-5H,6H2

92210-53-2Relevant academic research and scientific papers

Asymmetric Synthesis of Functionalized Tricyclic Chromanes via an Organocatalytic Triple Domino Reaction

Kumar, Mukesh,Chauhan, Pankaj,Valkonen, Arto,Rissanen, Kari,Enders, Dieter

, p. 3025 - 3028 (2017)

A highly stereoselective triple domino reaction for the synthesis of functionalized tricyclic chromane scaffolds has been developed. A secondary amine-catalyzed domino Michael/Michael/aldol condensation reaction between aliphatic aldehydes, nitro-chromene

Intensified synthesis of [3,4-d]triazole-fused chromenes, coumarins, and quinolones

Schwendt, Georg,Glasnov, Toma

, p. 69 - 75 (2017/01/17)

Abstract: Efficient and metal-free synthesis of [3,4-d]triazole-fused chromenes, coumarins, and quinolones has been achieved in an intensified regime using microwave heating. The smooth 1,3-dipolar cycloaddition reaction of heterocyclic nitroalkenes with

1,4-addition of TMSCCl3 to nitroalkenes: Efficient reaction conditions and mechanistic understanding

Wu, Na,Wahl, Benoit,Woodward, Simon,Lewis, William

supporting information, p. 7718 - 7724 (2014/07/07)

Improved synthetic conditions allow preparation of TMSCCl3 in good yield (70 %) and excellent purity. Compounds of the type NBu4X [X=Ph3SiF2 (TBAT), F (tetrabutylammonium fluoride, TBAF), OAc, Cl and Br] act as catalytic promoters for 1,4-additions to a range of cyclic and acyclic nitroalkenes, in THF at 0-25 °C, typically in moderate to excellent yields (37-95 %). TBAT is the most effective promoter and bromide the least effective. Multinuclear NMR studies (1H, 19F, 13C and 29Si) under anaerobic conditions indicate that addition of TMSCCl3 to TBAT (both 0.13 M) at -20 °C, in the absence of nitroalkene, leads immediately to mixtures of Me3SiF, Ph3SiF and NBu4CCl3. The latter is stable to at least 0 °C and does not add nitroalkene from -20 to 0 °C, even after extended periods. Nitroalkene, in the presence of TMSCCl3 (both 0.13 M at -20 °C), when treated with TBAT, leads to immediate formation of the 1,4-addition product, suggesting the reaction proceeds via a transient [Me 3Si(alkene)CCl3] species, in which (alkene) indicates an Si O coordinated nitroalkene. The anaerobic catalytic chain is propagated through the kinetic nitronate anion resulting from 1,4 CCl3 - addition to the nitroalkene. This is demonstrated by the fact that isolated NBu4[CH2=NO2] is an efficient promoter. Use of H2C=CH(CH2)2CH=CHNO 2 in air affords radical-derived bicyclic products arising from aerobic oxidation. Understanding TMSCCl3: The synthesis and reactivity of TMSCCl3 has been investigated. The mechanism of 1,4-CCl3 addition to nitroalkenes begins with nitroalkene coordination, followed by the attack of an external fluoride ion, and does not involve the formation of NBu4[Me3SiFCCl3] (see figure).

Assessment of dopamine D1 receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393

Clark, Alia H.,McCorvy, John D.,Watts, Val J.,Nichols, David E.

experimental part, p. 5420 - 5431 (2011/10/30)

To assess the effect of conformational mobility on receptor activity, the β-phenyl substituent of dopamine D1 agonist ligands of the phenylbenzazepine class, (±)-6,6a,7,8,9,13b-hexahydro-5H-benzo[d] naphtho[2,1-b]azepine-11,12-diol (8), and its oxygen and sulfur bioisosteres 9 and 10, respectively, were synthesized as conformationally-restricted analogs of SKF38393, a dopamine D1-selective partial agonist. Compounds trans-8b, 9, and 10 showed binding affinity comparable to that of SKF38393, but functionally, they displayed only very weak agonist activity. These results suggest that the conformationally-restricted structure of the analogs cannot adopt a binding orientation that is necessary for agonist activity.

Efficient conjugate addition of carbonyl compounds to 3-nitro-2H-chromenes in the presence of bases

Hu, Zhi-Peng,Zhang, Jun-Min,Lou, Chun-Liang,Wang, Jin-Jia,Nie, Shao-Zhen,Yan, Ming

experimental part, p. 17 - 33 (2011/03/17)

The conjugate addition of aldehydes and ketones to 3-nitro-2H-chromenes under basic conditions has been explored. A series of inorganic and organic bases were examined. Proline combined with NaOAc was found to act as an efficient catalyst for the reaction

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 92210-53-2