92210-56-5

Upstream product

• 3638-64-0 1-nitroethylene 
• 1761-61-1 5-bromosalicyclaldehyde 
• 625-48-9 2-nitro-1-ethanol 
• 18942-89-7 2-nitroethyl acetate 

Downstream Products

• 1370549-70-4 (6aS,13cR)-9-benzyl-2-bromo-6a-nitro-6,6a,7,8,9,13c-hexahydrochromeno[3,4-c]carbazole 

Relevant academic research and scientific papers

Asymmetric Synthesis of Functionalized Tricyclic Chromanes via an Organocatalytic Triple Domino Reaction

A highly stereoselective triple domino reaction for the synthesis of functionalized tricyclic chromane scaffolds has been developed. A secondary amine-catalyzed domino Michael/Michael/aldol condensation reaction between aliphatic aldehydes, nitro-chromene

Intensified synthesis of [3,4-d]triazole-fused chromenes, coumarins, and quinolones

Abstract: Efficient and metal-free synthesis of [3,4-d]triazole-fused chromenes, coumarins, and quinolones has been achieved in an intensified regime using microwave heating. The smooth 1,3-dipolar cycloaddition reaction of heterocyclic nitroalkenes with

Efficient conjugate addition of carbonyl compounds to 3-nitro-2H-chromenes in the presence of bases

The conjugate addition of aldehydes and ketones to 3-nitro-2H-chromenes under basic conditions has been explored. A series of inorganic and organic bases were examined. Proline combined with NaOAc was found to act as an efficient catalyst for the reaction

Inhibitors of farnesyl protein transferase

The present invention discloses the identification of the novel inhibitors of farnesyl protein transferase and ras protein farnesylation. The compounds and pharmaceutical compositions disclosed herein are useful in treating diseases associated with farnesyl protein transferase, such as cancer.

New Direct Synthesis of 3-Nitro-2H-chromenes Using Nitroethylene

The treatment of substituted 2-hydroxybenzaldehydes by nitroethylene, prealably prepared or generated in situ within the reaction, in the presence of di-n-butylamine gave 3-nitro-2H-chromenes in fair to excellent yields.