922163-75-5

Upstream product

• 922163-74-4 6,7-bis-benzyloxy-5-benzyloxymethyl-8-(tert-butyl-dimethyl-silanyloxy)-2-iodo-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine 
• 536-74-3 phenylacetylene 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 135910-13-3 (3R,4R,5R)-3,4,6-tris(benzyloxy)hexane-1,5-diol 
• 16838-89-4 2,3,5-tri-O-benzyl-L-xylofuranose 
• 922163-68-6 2,3,5-tris-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-1-(1-trityl-1H-imidazol-2-yl)-pentan-1-ol 
• 922163-70-0 benzoic acid 2,3,5-tris-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-1-(4,5-diiodo-1H-imidazol-2-yl)-pentyl ester 
• 922163-71-1 Benzoic acid (1R,2R,3R,4S)-2,3,5-tris-benzyloxy-1-(4,5-diiodo-1H-imidazol-2-yl)-4-hydroxy-pentyl ester 
• 922163-69-7 benzoic acid 2,3,5-tris-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-1-(1H-imidazol-2-yl)-pentyl ester 
• 922163-73-3 6,7-bis-benzyloxy-5-benzyloxymethyl-8-(tert-butyl-dimethyl-silanyloxy)-2,3-diiodo-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine 
• 922163-72-2 Benzoic acid (5R,6R,7S,8R)-6,7-bis-benzyloxy-5-benzyloxymethyl-2,3-diiodo-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-8-yl ester 
• 922499-10-3 (2R,3S,4S)-2,3,5-Tris-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-pentan-1-ol 
• 922163-66-4 (2S,3S,4S)-2,3,5-Tris-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-pentanal 

Downstream Products

• 922163-77-7 (5R,6R,7R,8S)-8-Azido-6,7-bis-benzyloxy-5-benzyloxymethyl-2-phenylethynyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine 
• 922163-78-8 N-(6,7-bis-benzyloxy-5-benzyloxymethyl-2-phenylethynyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-8-yl)-isobutyramide 
• 922163-76-6 (5R,6R,7R,8R)-6,7-Bis-benzyloxy-5-benzyloxymethyl-2-phenylethynyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-8-ol 

Relevant academic research and scientific papers

SELECTIVE GLYCOSIDASE INHIBITORS

The present invention provides glucoimidazole derivatives and methods of making them. The compounds can be used to inhibit the activity of O-GlcNAcase enzymes, including both bacterial OGA (bOGA) and human OGA (hOGA) and can be selective, showing low inhi

GlcNAcstatin: A picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-GlcNAcylation levels

Many phosphorylation signal transduction pathways in the eukaryotic cell are modulated by posttranslational modification of specific serines/threonines with N-acetylglucosamine (O-GlcNAc). Levels of O-GlcNAc on key proteins regulate biological processes a