92233-36-8Relevant academic research and scientific papers
Amethopterine (methotrexate) phosphonoglutamic analogues. Part II. Dihydrofolate reductase inhibition
Sturtz,Guillamot,Bourdeaux,Chauvet
, p. 274 - 276 (2007/10/02)
Following a description of the synthesis of the phosphonate-pteridines, this paper is a study of the experimental conditions needed for selective ester hydrolysis. Antimetabolic properties of these compounds versus D.H.F.R. were tested. An appreciable ant
