92235-77-3Relevant academic research and scientific papers
PYRROLIDINE RING FORMATION BY A NEW BASE-PROMOTED 1,3-DIPOLAR CYCLOADDITION OF N-(PHENYLTHIOMETHYL)AMINO ACID ESTERS
Imai, Nobuyuki,Terao, Yoshiyasu,Achiwa, Kazuo,Sekiya, Minoru
, p. 1579 - 1582 (1984)
N-Phenylthiomethyl derivatives of α-amino acid esters are attacked by α,β-unsaturated carboxylates in the presence of sodium hydride, undergoing 1,3-dipolar cycloaddition to give pyrrolidines.
Pyrrolidine-Forming 1,3-Dipolar Cycloaddition of N-(Phenylthiomethyl)-α-amino Acid Esters
Imai, Nobuyuki,Nemoto, Mari,Terao, Yoshiyasu,Achiwa, Kazuo,Sekiya, Minoru
, p. 1080 - 1088 (2007/10/02)
The sodium hydride-aided reaction of N-(phenylthiomethyl)-α-amino acid esters with α,β-unsaturated carboxylates results in a pyrrolidine-forming 1,3-dipolar cycloaddition.Thus, a new route to pyrrolidines, pyrrolizidines and indolizidines has been provide
A NEW SYNTHETIC METHOD FOR PROLINE DERIVATIVES VIA THE AZOMETHINE YLIDE INTERMEDIATE GENERATED FROM METHYL N-(TRIMETHYLSILYLMETHYL)IMINOACETATE
Imai, Nobuyuki,Terao, Yoshiyasu,Achiwa, Kazuo
, p. 1107 - 1110 (2007/10/02)
Proline derivatives were found to be synthesized by the 1,3-dipolar cycloaddition of the azomethine ylide, produced from methyl N-(trimethylsilylmethyl)iminoacetate and benzyl bromide or a catalytic amount of trifluoroacetic acid, to conjugated olefins.
