922491-01-8Relevant academic research and scientific papers
Stability and polymerase recognition of pyridine nucleobase analogues: Role of minor-groove H-bond acceptors
Kim, Yoonkyung,Leconte, Aaron M.,Hari, Yoshiyuki,Romesberg, Floyd E.
, p. 7809 - 7812 (2007/10/03)
In the groove: In an effort to develop unnatural base pairs, pyridyl nucleoside analogues were synthesized and characterized (see structures). An α-glycosidic nitrogen atom provides an H-bond acceptor that does not significantly facilitate pairing with na
