92251-49-5Relevant academic research and scientific papers
Palladium-catalyzed regiocontrolled α-arylation of trimethylsilyl enol ethers with aryl halides
Iwama, Tetsuo,Rawal, Viresh H.
, p. 5725 - 5728 (2007/10/03)
(Diagram presented) Inter- and intramolecular arylations of trimethylsilyl enol ethers with aryl halides are accomplished regiospecifically in the presence of a palladium catalyst and tributyltin fluoride in refluxing benzene or toluene. The optimal catalyst system called for the use of Pd 2(dba)3 and tri-tert-butylphosphine in ca. 1:2 ratio. Aryl iodides, bromides, and chlorides are all effective arylation partners in this reaction.
