922716-09-4

Basic information

• Product Name: 12-hydroxy-11-(3-chlorobenzoyloxy)-abieta-8,11,13-triene
• CAS NO: 922716-09-4
• Molecular Weight: 441.01
• Mol File: 922716-09-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12-hydroxy-11-(3-chlorobenzoyloxy)-abieta-8,11,13-triene(CAS DataBase Reference)
• NIST Chemistry Reference: 12-hydroxy-11-(3-chlorobenzoyloxy)-abieta-8,11,13-triene(922716-09-4)
• EPA Substance Registry System: 12-hydroxy-11-(3-chlorobenzoyloxy)-abieta-8,11,13-triene(922716-09-4)

Safety Data

• Hazardous Substances Data: 922716-09-4(Hazardous Substances Data)

Upstream product

• 845-30-7 m-chlorobenzoyl peroxide 
• 514-62-5 ferruginol 

Relevant articles and documents

Syntheses and antibacterial activities of diterpene catechol derivatives with abietane, totarane and podocarpane skeletons against methicillin-resistant Staphylococcus aureus and Propionibacterium acnes

Natural catechol, quinone and quinone methide diterpenes with abietane (15-deoxyfuerstione, taxodione) and totarane (dispermone, 12,13-dihydroxy-8,11, 13-totaratriene-6-one), and podocarpane (nimbidiol, deoxynimbidiol) skeletons were synthesized using ortho-oxidation of phenol with meta-chlorobenzoyl peroxide. Minimum inhibitory activities of these diterpenes and previously synthesized natural diterpenes were measured against methicillin-resistant Staphylococcus aureus (MRSA) and Propionibacterium acnes, which cause serious skin infection associated with acne. Abietaquinone methide and 8,11,13-totaratriene-12,13-diol showed potent activities against S. aureus (MRSA) and P. acnes, and no serious toxicity by oral dose to mice.