92278-33-6Relevant articles and documents
Synthesis of (S) and (R) O-Benzyl-lactaldehyde
Fuganti, Claudio,Grasselli, Piero,Servi, Stefano,Spreafico, Franca,Zirotti, Carlo
, p. 976 - 984 (2007/10/02)
(3S,4S) 3,4-Isopropylidendioxypentan-2-one (6) is reduced by metal hydrides to (2S,3R,4S) 3,4-isopropylidendioxypentan-2-ol (7) and to the (2R,3R,4S) isomer (9), subsequently converted into (S) and (R) O-benzyl-lactaldehyde (4) and (5); (S) and (R) O-benzyl-lactaldehyde (4) and (5); (S) O-benzyl-lactaldehyde (4) is also obtained in ca. 90percent ee from (2S) 4-phenylbut-3-en-2-ol (16), prepared by baker's yeast reduction of benzylideneacetone (15).