923259-70-5 Usage
Uses
Used in Organic Synthesis:
6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is used as a key intermediate in organic synthesis for the creation of complex organic molecules. Its unique trifluoromethoxy group and indole core provide a foundation for the development of new chemical entities with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is utilized as a precursor in the synthesis of drugs with potential therapeutic applications. Its presence in drug molecules can impart beneficial pharmacological effects, making it a valuable component in medicinal chemistry.
Used in Drug Development:
6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is employed in drug development for its potential to treat various diseases and disorders. Its biological activities are under investigation, and it may contribute to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Overall, 6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is a significant chemical entity with a broad spectrum of applications in the fields of organic synthesis, pharmaceutical research, and drug development, highlighting its importance in advancing medical science.
Check Digit Verification of cas no
The CAS Registry Mumber 923259-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,2,5 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 923259-70:
(8*9)+(7*2)+(6*3)+(5*2)+(4*5)+(3*9)+(2*7)+(1*0)=175
175 % 10 = 5
So 923259-70-5 is a valid CAS Registry Number.
923259-70-5Relevant academic research and scientific papers
Knerr, Laurent,Giordanetto, Fabrizio,Nordberg, Peter,Pettersen, Daniel,Selmi, Nidhal,Beisel, Hans-Georg,De La Motte, Hannah,Olsson, Thomas,Perkins, Tim D. J.,Hersl?f, Margareta,M?nsson, ?sa,Dahlstr?m, Mikael,Starke, Ingemar,Broddefalk, Johan,Saarinen, Gabrielle,Klingeg?rd, Fredrik,Hurt-Camejo, Eva,Rosengren, Birgitta,Brengdahl, Johan,Jansen, Frank,Rohman, Mattias,Sandmark, Jenny,Hallberg, Kenth,?kerud, Tomas,Roth, Robert G.,Ahlqvist, Marie
, p. 594 - 599 (2018)
In order to assess the potential of sPLA2-X as a therapeutic target for atherosclerosis, novel sPLA2 inhibitors with improved type X selectivity are required. To achieve the objective of identifying such compounds, we embarked on a lead generation effort that resulted in the identification of a novel series of indole-2-carboxamides as selective sPLA2-X inhibitors with excellent potential for further optimization.
