923259-70-5 Usage
General Description
6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is a chemical compound that belongs to the class of indole derivatives. It is a white to off-white powder with a molecular formula of C11H7F3N2O3. 6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is used in the field of organic synthesis and pharmaceutical research, as it has potential biological activities and can be used as a building block in the synthesis of various pharmaceutical drugs. Additionally, it has been studied for its potential use in the treatment of various diseases and disorders. Overall, 6-(trifluoromethoxy)-1H-indole-2-carboxylic acid is a valuable chemical compound with potential applications in the field of medicine and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 923259-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,2,5 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 923259-70:
(8*9)+(7*2)+(6*3)+(5*2)+(4*5)+(3*9)+(2*7)+(1*0)=175
175 % 10 = 5
So 923259-70-5 is a valid CAS Registry Number.
923259-70-5Relevant articles and documents
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors
Knerr, Laurent,Giordanetto, Fabrizio,Nordberg, Peter,Pettersen, Daniel,Selmi, Nidhal,Beisel, Hans-Georg,De La Motte, Hannah,Olsson, Thomas,Perkins, Tim D. J.,Hersl?f, Margareta,M?nsson, ?sa,Dahlstr?m, Mikael,Starke, Ingemar,Broddefalk, Johan,Saarinen, Gabrielle,Klingeg?rd, Fredrik,Hurt-Camejo, Eva,Rosengren, Birgitta,Brengdahl, Johan,Jansen, Frank,Rohman, Mattias,Sandmark, Jenny,Hallberg, Kenth,?kerud, Tomas,Roth, Robert G.,Ahlqvist, Marie
, p. 594 - 599 (2018)
In order to assess the potential of sPLA2-X as a therapeutic target for atherosclerosis, novel sPLA2 inhibitors with improved type X selectivity are required. To achieve the objective of identifying such compounds, we embarked on a lead generation effort that resulted in the identification of a novel series of indole-2-carboxamides as selective sPLA2-X inhibitors with excellent potential for further optimization.