923289-10-5

Basic information

• Product Name: C₂₉H₃₇N₃O₈
• Synonyms: C₂₉H₃₇N₃O₈
• CAS NO: 923289-10-5
• Molecular Weight: 555.628
• Mol File: 923289-10-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₇N₃O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₇N₃O₈(923289-10-5)
• EPA Substance Registry System: C₂₉H₃₇N₃O₈(923289-10-5)

Safety Data

• Hazardous Substances Data: 923289-10-5(Hazardous Substances Data)

Upstream product

• 923289-03-6 C₂₂H₃₄N₂O₅ 
• 62-23-7 4-nitro-benzoic acid 

Relevant articles and documents

MACROCYLIC INHIBITORS OF HEPATITIS C VIRUS

Inhibitors of HCV of formula (I), and the N-oxides, salts, and stereochemically isomeric forms thereof, wherein R1 is aryl or a saturated, a partially unsaturated or completely unsaturated 5 or 6 membered monocyclic or 8 to 12 membered bicyclic heterocyclic ring system containing one nitrogen, and optionally one to three oxygen, sulfur or nitrogen, wherein said ring system may be optionally substituted; L is a direct bond, -O-. -O-C1-4alkanediyl-, -O-CO-, -O-C(=O)-NR5a- or -O-C(=O)-NR5a-C1-4alkanediyl-; R2 is hydrogen, -OR6, -C(O)OR6, -C(=O)R7, -C(=O)NR5aR5b, -C(=O)NHR5c, -NR5aR5b, -NHR5c, -NHSOpNR5aR5b, -NR5aSOpR8, or -B(OR6)2; R3 and R4 are hydrogen or C1-6alkyl; or R3 and R4 taken together may form a C3-7cycloalkyl ring; n is 3, 4, 5, or 6; p is 1 or 2; aryl is phenyl, naphthyl, indanyl, or 1,2,3,4-tetrahydronaphthyl, each of which may be optionally substituted Het is a 5 or 6 membered saturated, partially unsaturated or completely unsaturated heterocyclic ring containing 1 to 4 heteroatoms each independently selected from nitrogen, oxygen and sulfur, being optionally condensed with a benzene ring, and wherein the group Het as a whole may be optionally substituted ; pharmaceutical compositions containing compounds (I) and processes for preparing compounds (I). Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.