923565-83-7 Usage
Chemical class
1-Propanone,
1-[4-[(4-fluorophenyl)amino]-1-piperidinyl]-3-[4-(hydroxymethyl)phenyl]- is a ketone, which is an organic compound with a carbonyl group (C=O) bonded to two alkyl or aryl groups.
Structure
The compound contains a piperidine ring, which is a nitrogen-containing six-membered heterocyclic ring, and is substituted with a fluorophenylamino group and a hydroxymethylphenyl group.
Functional groups
The compound has a ketone group (C=O), a piperidine ring (N-containing 6-membered ring), a fluorophenyl group (a phenyl ring with a fluorine atom), and a hydroxymethyl group (a methyl group with a hydroxyl group).
Applications
The compound is used in pharmaceutical research and drug development, particularly for its potential analgesic and neuroprotective properties.
Potential applications
The compound may have potential applications in the treatment of pain and neurological disorders, making it a promising candidate for further investigation in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 923565-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,5,6 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 923565-83:
(8*9)+(7*2)+(6*3)+(5*5)+(4*6)+(3*5)+(2*8)+(1*3)=187
187 % 10 = 7
So 923565-83-7 is a valid CAS Registry Number.
923565-83-7Relevant academic research and scientific papers
Discovery of N-(3-fluorophenyl)-1-[(4-([(35)-3-methyl-1-piperazinyl]methyl) phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate
Westaway, Susan M.,Brown, Samantha L.,Fell, Stephen C. M.,Johnson, Christopher N.,MacPherson, David T.,Mitchell, Darren J.,Myatt, James W.,Stanway, Steven J.,Seal, Jon T.,Stemp, Geoffrey,Thompson, Mervyn,Lawless, Kirk,McKay, Fiona,Muir, Alison I.,Barford, Jonathan M.,Cluff, Chermaine,Mahmood, Sadhia R.,Matthews, Kim L.,Mohamed, Shiyam,Smith, Beverley,Stevens, Alexander J.,Bolton, Victoria J.,Jarvie, Emma M.,Sanger, Gareth J.
experimental part, p. 1180 - 1189 (2010/01/16)
N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl) acetyl]-4-piperidinamine 12 (GSK962040) is a novel small molecule motilin receptor agonist. It possesses excellent activity at the recombinant human motilin receptor and also at the native rabbit motilin receptor where its agonist activity results in potentiation of the amplitude of neuronal-mediated contractions of isolated gastric antrum tissue. Compound 12 also possesses highly promising pharmacokinetic profiles in both rat and dog, and these results, in combination with further profiling in human native tissue and an in vivo model of gastrointestinal transit in the rabbit, have led to its selection as a candidate for further development.
