92357-82-9Relevant academic research and scientific papers
Syntheses of Asymmetrical Diaryl and Aryl Alkyl Ketones as Possible Non-steroidal Antiprogestational Agents
Kumar, Shiv,Seth, M.,Bhaduri, A. P.,Agnihotri, Anila,Srivastava, A. K.
, p. 154 - 157 (2007/10/02)
A number of asymmetrical diaryl and aryl alkyl ketones have been synthesised as possible non-steroidal antiprogestational agents.Evaluation of these compounds as competitive inhibitors of progesterone binding to uterine cytosol progesterone receptors of rabbit and human indicates that 3-methyl-4'-phenylbenzophenone (2) exhibits marginal activity in both the cases.However, this compound has been found to be inferior to R 5020 and d-norgestrel.
