923579-13-9

Basic information

• Product Name: methyl (R)-2-benzyl-3-[2-(tert-butyldimethylsilyloxy)-ethylamino]-2-(2-nitrobenzenesulfonylamino)-propanoate
• Synonyms: methyl (R)-2-benzyl-3-[2-(tert-butyldimethylsilyloxy)-ethylamino]-2-(2-nitrobenzenesulfonylamino)-propanoate
• CAS NO: 923579-13-9
• Molecular Weight: 551.736
• Mol File: 923579-13-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (R)-2-benzyl-3-[2-(tert-butyldimethylsilyloxy)-ethylamino]-2-(2-nitrobenzenesulfonylamino)-propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-2-benzyl-3-[2-(tert-butyldimethylsilyloxy)-ethylamino]-2-(2-nitrobenzenesulfonylamino)-propanoate(923579-13-9)
• EPA Substance Registry System: methyl (R)-2-benzyl-3-[2-(tert-butyldimethylsilyloxy)-ethylamino]-2-(2-nitrobenzenesulfonylamino)-propanoate(923579-13-9)

Safety Data

• Hazardous Substances Data: 923579-13-9(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 923578-94-3 methyl (R)-2-amino-2-benzyl-3-hydroxypropanoate 
• 923578-97-6 (2R)-2-benzyl-2-methoxycarbonyl-1-(2-nitrobenzenesulfonyl)-aziridine 
• 101711-55-1 2‐((tert‐butyldimethylsilyl)oxy)ethan‐1‐amine 

Downstream Products

• 923579-02-6 (3R)-3-benzyl-1-[2-(tert-butyldimethylsilyloxy)-ethyl]-3-(2-nitrobenzenesulfonylamino)-azetidin-2-one 

Relevant articles and documents

Synthesis of β-lactam scaffolds for ditopic peptidomimetics

(Chemical Equation Presented) Ring opening of α-substituted-α- methoxycarbonyl-N-nosylaziridines provides a practical access to enantiopure α,α′-disubstituted β-lactam scaffolds, novel types of ditopic reverse turn surrogates. The procedure is general, short, and high yielding and starts from handy α-substituted serinates and α-amino acid derivatives.