923934-25-2Relevant academic research and scientific papers
On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A
Wenzel, Silke C.,Williamson, Rachel M.,Gruenanger, Christian,Xu, Jun,Gerth, Klaus,Martinez, Rodolfo A.,Moss, Steven J.,Carroll, Brian J.,Grond, Stephanie,Unkefer, Clifford J.,Mueller, Rolf,Floss, Heinz G.
, p. 14325 - 14336 (2008/03/13)
Feeding experiments with isotope-labeled precursors rule out hydroxypyruvate and TCA cycle intermediates as the metabolic source of methoxymalonyl-ACP, the substrate for incorporation of "glycolate" units into ansamitocin P-3, soraphen A, and other antibi
