923949-16-0

Upstream product

• 923949-15-9 (4S)-4-benzyl-3-[(2E)-3-(5-chloropyridin-2-yl)prop-2-enoyl]-1,3-oxazolidin-2-one 

Downstream Products

• 923949-17-1 methyl (3S,4S)-1-benzyl-4-(5-chloropyridin-2-yl)pyrrolidine-3-carboxylate 
• 924011-97-2 (3S,4S)-1-benzyl-4-(5-chloropyridin-2-yl)pyrrolidine-3-carboxylic acid 

Relevant academic research and scientific papers

MELANOCORTIN TYPE 4 RECEPTOR AGONIST PIPERIDINOYLPYRROLIDINES

The present invention relates to a class of melanocortin MCR4 agonists of general formula (I), wherein the variables and substituents are as defined herein and especially to selective MCR4 agonist compounds, to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.

PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS

The present invention relates to a class of compounds of general formula (I) and the salts, hydrates, solvates, polymorphs and prodrugs wherein n, R6, R7 and R10 are as defined herein and especially to MCR4 agonist compounds of formula (I), to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.