923973-17-5Relevant academic research and scientific papers
Syntheses of N10-substituted 7-arylpyrrolo[2,1-c]-[1,4]benzodiazepine-5,11- diones
Lindner, Anika Sabine,Geist, Egor,Gjikaj, Mimoza,Schmidt, Andreas
, p. 423 - 431 (2014)
Pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione and its 7-bromo derivative were alkylated at the N10 atom applying various methods. The resulting products were subjected to Suzuki-Miyaura reactions using a catalyst system consisting of Pd(Cl)2(PPh3)2 and sodium tert-butanolate in toluene. Results of an X-ray single crystal analysis are presented.
