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Centanafadine HCl is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) that is currently in phase II clinical trials.

923981-14-0

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923981-14-0 Usage

Uses

Used in Pharmaceutical Industry:
Centanafadine HCl is used as a treatment for attention deficit hyperactivity disorder (ADHD) due to its ability to inhibit the reuptake of serotonin, norepinephrine, and dopamine, which are neurotransmitters involved in regulating mood, attention, and impulse control.

Check Digit Verification of cas no

The CAS Registry Mumber 923981-14-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,9,8 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 923981-14:
(8*9)+(7*2)+(6*3)+(5*9)+(4*8)+(3*1)+(2*1)+(1*4)=190
190 % 10 = 0
So 923981-14-0 is a valid CAS Registry Number.

923981-14-0Downstream Products

923981-14-0Relevant articles and documents

NOVEL MANUFACTURING METHOD

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Paragraph 0027, (2019/10/04)

PROBLEM TO BE SOLVED: To provide a manufacturing method providing high optical purity, having inexpensive price and easily being handled in industrial manufacturing of a final product material having excellent biological activity. SOLUTION: There is provi

CRYSTALLINE COMPOUNDS

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Paragraph 00246, (2017/01/02)

The present invention relates to crystalline forms of (1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochloride and compositions comprising the same and methods of making and using the same.

USE OF (1R,5S)-(+)-1-(NAPHTHALEN-2-YL)-3-AZABICYCLO{3.1.0}HEXANE IN THE TREATMENT OF CONDITIONS AFFECTED BY MONOAMINE NEUROTRANSMITTERS

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Paragraph 00110-00111, (2013/03/26)

The present invention relates to (lR,5S)-(+)-l-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane and pharmaceutical compositions thereof, and methods employing their use in the treatment of conditions affected by monoamine neurotransmitters, including ADHD and

METHODS AND COMPOSITIONS FOR PRODUCTION, FORMULATION AND USE OF 1 ARYL -3-AZABICYCLO[3.1.0 ] HEXANES

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Page/Page column 46, (2010/11/30)

The invention provides novel compositions and methods of making (-)-1-(3,4- dichlorophenyl)-3-azabicyclo[3.1.0]hexane and other 1-aryl-3- azabicyclo[3.1.0]hexanes, including synthetic methods that form novel intermediate compounds of the invention for pro

NOVEL 1-ARYL-3-AZABICYCLO[3.1.0]HEXANES: PREPARATION AND USE TO TREAT NEUROPSYCHIATRIC DISORDERS

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Page/Page column 164, (2008/06/13)

The invention provides novel, multiply-substituted l-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.

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