92400-78-7

Basic information

• Product Name: 3-(4-chlorophenyl)-4-methyl-1,2,4-oxadiazol-5(4H)-one
• Synonyms: 3-(4-chlorophenyl)-4-methyl-1,2,4-oxadiazol-5(4H)-one
• CAS NO: 92400-78-7
• Molecular Weight: 210.62
• Mol File: 92400-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-chlorophenyl)-4-methyl-1,2,4-oxadiazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-4-methyl-1,2,4-oxadiazol-5(4H)-one(92400-78-7)
• EPA Substance Registry System: 3-(4-chlorophenyl)-4-methyl-1,2,4-oxadiazol-5(4H)-one(92400-78-7)

Safety Data

• Hazardous Substances Data: 92400-78-7(Hazardous Substances Data)

Upstream product

• 5033-28-3 4-chlorobenzamidoxime 
• 186581-53-3 diazomethane 
• 19932-93-5 3-(4-chloro-phenyl)-4H-[1,2,4]oxadiazol-5-one 

Relevant articles and documents

Rh(II)-Catalyzed Transannulation of 1,2,4-Oxadiazole Derivatives with 1-Sulfonyl-1,2,3-triazoles: Regioselective Synthesis of 5-Sulfonamidoimidazoles

An effective method for the synthesis of fully substituted 5-sulfonamidoimidazoles by Rh(II)-catalyzed transannulation of 1,2,4-oxadiazole derivatives with N-sulfonyl-1,2,3-triazoles is reported. The reaction works well with both aromatic 1,2,4-oxadiazoles and 1,2,4-oxadiazol-5-ones providing a flexible approach to N-(alkoxy/amino)carbonyl- and N-alkyl-substituted imidazoles. Both the disclosed reactions are completely regioselective and provide the first examples of a carbenoid-mediated transformation of N,N,O-heterocycles.