92406-41-2

Usage

Uses

Used in Pharmaceutical Research and Development:
1H-Pyrazol-5-amine, 3-cyclobutyl-1-methylis used as a building block for the synthesis of potential drug candidates due to its diverse pharmacological activities.
Used in Anti-inflammatory and Analgesic Applications:
1H-Pyrazol-5-amine, 3-cyclobutyl-1-methylis used as a potential anti-inflammatory and analgesic agent, as it has been studied for its potential to exhibit these properties.

Upstream product

• 118431-89-3 β-Cyclobutyl-β-oxopropionitrile 
• 60-34-4 methylhydrazine 

Downstream Products

• 606129-58-2 (5-cyclobutyl-2-methyl-2H-pyrazol-3-yl)-carbamic acid phenyl ester 
• 92388-32-4 4,7-dihydro-1,6-dimethyl-4-(3-nitrophenyl)-3-(cyclobutyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS

The present disclosure provides substituted 9H-pyrimido[4,5-b]indoles and 5H-pyrido[4,3-b]indoles and related analogs represented by Formula I: and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1a, A, B1, B2, G, X1, Y1, Y2, and Y3 are as defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a condition or disorder responsive to inhibition of BET bromodomains. Compounds of the present disclosure are especially useful for treating cancer.

1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES

Compounds of formula Ia or Ib in free or salt form, wherein Ar, X1, X2, m, R1, Q, Y, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by CCR-3, for example an inflammatory or allergic cond