92424-72-1 Usage
Class
Benzofuran derivatives
Use
Treatment for transthyretin amyloidosis
Mechanism of Action
Stabilizes abnormal protein, preventing its harmful effects on the body and slowing down the progression of the disease
Potential Applications
Treating other neurodegenerative diseases
Administration
Orally, in the form of a tablet
Approval
Approved for medical use in several countries
Check Digit Verification of cas no
The CAS Registry Mumber 92424-72-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,2 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 92424-72:
(7*9)+(6*2)+(5*4)+(4*2)+(3*4)+(2*7)+(1*2)=131
131 % 10 = 1
So 92424-72-1 is a valid CAS Registry Number.
92424-72-1Relevant academic research and scientific papers
The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening
Odell, Luke R.,Howan, Dian,Gordon, Christopher P.,Robertson, Mark J.,Chau, Ngoc,Mariana, Anna,Whiting, Ainslie E.,Abagyan, Ruben,Daniel, James A.,Gorgani, Nick N.,Robinson, Phillip J.,McCluskey, Adam
experimental part, p. 5267 - 5280 (2010/10/18)
We report the development of a homology model for the GTP binding domain of human dynamin I based on the corresponding crystal structure of Dictyostelium discoidum dynamin A. Virtual screening identified 2-[(2-biphenyl-2-yl-1,3-dioxo- 2,3-dihydro-1H-isoin
