924287-02-5Relevant articles and documents
Benzothiazole based inhibitors of p38α MAP kinase
Liu, Chunjian,Lin, James,Pitt, Sidney,Zhang, Rosemary F.,Sack, John S.,Kiefer, Susan E.,Kish, Kevin,Doweyko, Arthur M.,Zhang, Hongjian,Marathe, Punit H.,Trzaskos, James,Mckinnon, Murray,Dodd, John H.,Barrish, Joel C.,Schieven, Gary L.,Leftheris, Katerina
, p. 1874 - 1879 (2008/12/21)
Rational design, synthesis, and SAR studies of a novel class of benzothiazole based inhibitors of p38α MAP kinase are described. The issue of metabolic instability associated with vicinal phenyl, benzo[d]thiazol-6-yl oxazoles/imidazoles was addressed by t
BENZOTHIAZOLE AND AZABENZOTHIAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS
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Page/Page column 79, (2008/06/13)
A compound of Formula (I), or an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, wherein A is independently selected from: (a); (b); (c); or (d), further wherein R1, R2, R3, R4, R5, R6, R7, and W are as described herein. Also discl