924288-49-3Relevant academic research and scientific papers
Total synthesis of antibiotics GE2270A and GE2270T
Nicolaou,Zou, Bin,Dethe, Dattatraya H.,Li, Dong Bo,Chen, David Y.-K.
, p. 7786 - 7792 (2007/10/03)
(Chemical Equation Presented) Beat the bugs: Total syntheses of the thiopeptide antibiotics GE2270A (X-Y = CH2-CH) and GE2270T (X-Y = CH= C) have been accomplished. The modular approach featured a hetero-Diels-Alder dimerization Circled latin capital letter A to construct the trithiazolyl pyridine domain, and highly regioselective macrolactamizations Circled latin capital letter B to furnish the macrocyclic core.
