N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine is a chemical compound that serves as an intermediate in the synthesis of 2-guanidino-4-arylquinazolines. These synthesized compounds are known for their potential as inhibitors of the sodium/proton exchanger NHE3.
92434-13-4
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Basic information
- Product Name: N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine
- Synonyms: N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine
- CAS NO:92434-13-4
- Molecular Formula: C15H12ClN5
- Molecular Weight: 297.74228
- EINECS: N/A
- Product Categories: N/A
- Mol File: 92434-13-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine(CAS DataBase Reference)
- NIST Chemistry Reference: N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine(92434-13-4)
- EPA Substance Registry System: N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine(92434-13-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 92434-13-4(Hazardous Substances Data)
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92434-13-4 Usage
Uses
Used in Pharmaceutical Industry:N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine is used as a chemical intermediate for the preparation of 2-guanidino-4-arylquinazolines. These compounds are synthesized for their potential application as inhibitors of the sodium/proton exchanger NHE3, which plays a crucial role in the regulation of intracellular pH and sodium balance. Inhibition of NHE3 can have therapeutic benefits in treating conditions associated with disrupted pH balance and sodium transport, such as hypertension and certain gastrointestinal disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 92434-13-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,3 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.Calculate Digit Verification of CAS Registry Number 92434-13:
(7*9)+(6*2)+(5*4)+(4*3)+(3*4)+(2*1)+(1*3)=124
124 % 10 = 4
So 92434-13-4 is a valid CAS Registry Number.
92434-13-4Upstream product
92434-13-4Downstream Products
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N-(6-Chloro-4-phenylquinazolin-2-yl)guanidine
