92437-29-1 Usage
Family
Quinazolinone
Function
Selective endothelin A receptor antagonist
Mechanism
Blocks the action of the endothelin A receptor, which is involved in blood vessel constriction and cell proliferation
Cardiovascular conditions
Treating pulmonary hypertension and heart failure
Inflammatory conditions
Treating acute kidney injury
Improving blood flow
In ischemic tissues
Reducing inflammation and fibrosis
In various disease states
Research Status
Studied for its potential use in treating the above-mentioned conditions
Clinical Applications
Promising candidate for further research and potential clinical applications due to its pharmacological properties
Check Digit Verification of cas no
The CAS Registry Mumber 92437-29-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,3 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 92437-29:
(7*9)+(6*2)+(5*4)+(4*3)+(3*7)+(2*2)+(1*9)=141
141 % 10 = 1
So 92437-29-1 is a valid CAS Registry Number.
92437-29-1Relevant academic research and scientific papers
Synthesis of 1-substituted 4(1H)-quinazolinones under solvent-free conditions
Wang, Yao,Zhang, Mei,Cao, Shengli,Lin, Huihui,Gao, Man,Li, Zhongfeng
experimental part, p. 2715 - 2727 (2012/07/14)
(Chemical Equation Presented) Heating a mixture of 2-(N-alkylamino)benzoic acids, triethyl orthoformate, and ammonium acetate under solvent-free conditions generated 1-substituted 4(1H)- quinazolinones in 73-99% yields. Moreover, a possible reaction pathway was proposed. Copyright Taylor & Francis Group, LLC.
