92453-47-9

Basic information

• Product Name: 3-(4-CHLORO-3-NITRO-PHENYL)-5-METHYL-[1,2,4]OXADIAZOLE
• Synonyms: 3-(4-CHLORO-3-NITRO-PHENYL)-5-METHYL-[1,2,4]OXADIAZOLE;AKOS BB-7515
• CAS NO: 92453-47-9
• Molecular Formula: C₉H₆ClN₃O₃
• Molecular Weight: 239.62
• Mol File: 92453-47-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-CHLORO-3-NITRO-PHENYL)-5-METHYL-[1,2,4]OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-CHLORO-3-NITRO-PHENYL)-5-METHYL-[1,2,4]OXADIAZOLE(92453-47-9)
• EPA Substance Registry System: 3-(4-CHLORO-3-NITRO-PHENYL)-5-METHYL-[1,2,4]OXADIAZOLE(92453-47-9)

Safety Data

• Hazardous Substances Data: 92453-47-9(Hazardous Substances Data)

Upstream product

• 862298-33-7 N'-acetyloxy-4-chloro-3-nitrobenzenecarboximideamide 

Downstream Products

• 862298-36-0 2,2-dimethyl-5-[4-(5-methyl-1, 2, 4-oxadiazol-3-yl)-2-nitrophenoxy]-4H-1, 3-benzodioxin-4-one 

Relevant articles and documents

((11-OXO-10,11-DIHYDRODIBENZO [B, F] [1, 4] OXAZEPIN-1-YL)OXY) ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS CARDIOVASCULAR PREPARATIONS USED TO TREAT ARTERIOLOSCLEROSIS

The invention relates to dibenzoxazepines and to a method for the production thereof, use thereof in the treatment and/or prophylaxis of illnesses, in addition to the use thereof in the production of medicaments for treating and/or for the prophylaxis of diseases, in particular cardiovascular illnesses, e.g. arteriolosclerosis, and cancers: Said dibenzoxazepines are represented by formula (I), wherein R2 represents C1-C6-alkyl, alkyl can be substituted by 1 or 2 substituents, said substituents are selected independently from each other from the group consisting of halogen, hydroxy, oxo, C1-C6-alkoxy, hydroxycarbonyl, C1-C6-alkoxycarbonyl, aminocarbonyl and C1-C6-alkylaminocarbonyl, R3 represents O-CH2CO2H or -O-(CH2)2CO2H, R5 represents 5- 10-membered heteroaryl, -SO2-R6 or -NR7(C=O)R8, whereby heteroaryl can be substituted by 1, 2 or 3 substituents, said substituents being selected independently from each other from the group consisting of halogen, trifluoromethyl, trifluoromethoxy, cyano, nitro, amino, C1-C6 alkylamino, hydroxy, C1-C6-alkyl, C1-C6-aIkoxy, hydroxycarbonyl, C1-C6-alkoxycarbonyl, amino-carbonyl, C1-C6-alkylaminocarbonyl, C6-C10-aryl and C3-C8-aycloalkyl. The other substituents are defined in the claims.