924633-99-8Relevant academic research and scientific papers
Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers
Chowdhury, Morshed Alam,Dong, Ying,Chen, Qiao-Hong,Abdellatif, Khaled R.A.,Knaus, Edward E.
, p. 1948 - 1956 (2008/09/21)
A group of 1-(aminosulfonylphenyl and methylsulfonylphenyl)-2-(pyridyl)acetylene regioisomers were designed such that a COX-2 SO2NH2 pharmacophore was located at the para-position of the phenyl ring, or a SO2Me pharmacopho
Halocyclization of 2-alkynylthioanisoles by cupric halides: synthesis of 2-substituted 3-halobenzo[b]thiophenes
Lu, Wen-Der,Wu, Ming-Jung
, p. 356 - 362 (2007/10/03)
Reaction of 2-alkynylthioanisoles 3 with 2 equiv of CuX2 (X=Br or Cl) in refluxing CH3CN for 2.5 h gave the 2-substituted 3-halobenzo[b]thiophenes 4 in good yields.
