924654-51-3Relevant academic research and scientific papers
2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists
Shireman, Brock T.,Dvorak, Curt A.,Rudolph, Dale A.,Bonaventure, Pascal,Nepomuceno, Diane,Dvorak, Lisa,Miller, Kirsten L.,Lovenberg, Timothy W.,Carruthers, Nicholas I.
, p. 2103 - 2108 (2008/09/20)
The synthesis and SAR for a novel series of 2-alkyl-4-aryl-tetrahydro-pyrido-pyrimidines and 2-alkyl-4-aryl-tetrahydro-pyrimido-azepines is described. Representative compounds were shown to be subtype selective 5-HT2A antagonists. Optimal place
PYRIMIDINE COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS
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Page/Page column 15, (2008/06/13)
Certain pyrimidine-containing compounds are serotonin receptor modulators useful in the treatment of serotonin-mediated diseases.
