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1H-Indole, 1-[3,5-bis(trifluoromethyl)phenyl]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

924659-06-3

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924659-06-3 Usage

Indole derivative

Heterocyclic aromatic organic compound
The compound is derived from the indole structure, which is an aromatic organic compound containing a heterocyclic ring (a ring containing more than one type of atom).

Trifluoromethylphenyl group

Attached to the 1-position of the indole ring
A trifluoromethyl group (CF3) is attached to the first position of the indole structure, which is known for its electron-withdrawing properties.

Electron-withdrawing properties

Influence on chemical and pharmaceutical applications
The presence of the electron-withdrawing trifluoromethyl group makes the compound potentially useful in various chemical and pharmaceutical applications, such as synthesis of organic compounds or development of new drugs and agrochemicals.

Building block and starting material

Synthesis and development
The compound may be used as a building block in the synthesis of organic compounds or as a starting material for the development of new drugs or agrochemicals.

Influence on physical and chemical properties

Technical and industrial processes
The presence of the trifluoromethyl group may also influence the compound's physical and chemical properties, making it useful in certain technical and industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 924659-06-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,4,6,5 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 924659-06:
(8*9)+(7*2)+(6*4)+(5*6)+(4*5)+(3*9)+(2*0)+(1*6)=193
193 % 10 = 3
So 924659-06-3 is a valid CAS Registry Number.

924659-06-3Downstream Products

924659-06-3Relevant academic research and scientific papers

Metal-free regioselective C-3 acetoxylation of N-substituted indoles: Crucial impact of nitrogen-substituent

Soni, Vineeta,Patel, Ulhas N.,Punji, Benudhar

, p. 57472 - 57481 (2015)

A metal-free method for the regioselective C-3 acetoxylation of the N-substituted indoles with PhI(OAc)2 is described under mild reaction conditions. This method tolerates a broad range of functional groups with moderate to good yields. The π-e

Improved Buchwald-Hartwig Amination by the Use of Lipids and Lipid Impurities

Bayer, Annette,Gevorgyan, Ashot,Hopmann, Kathrin H.

supporting information, (2021/11/12)

The development of green Buchwald-Hartwig aminations has long been considered challenging, due to the high sensitivity of the reaction to the environment. Here we show that food-grade and waste vegetable oils, triglycerides originating from animals, and natural waxes can serve as excellent green solvents for Buchwald-Hartwig amination. We further demonstrate that amphiphiles and trace ingredients present in triglycerides as additives have a decisive effect on the yields of Buchwald-Hartwig aminations.

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