Basic information

Product Name: Amrubicinhydrochloride
Synonyms: Amrubicin HCL;(7S-cis)-9-Acetyl-9-amino-7-[(2-deoxy-alpha-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione hydrochloride
CAS NO:92470-31-0
Molecular Formula: C25H25NO9.HCl
Molecular Weight: 519.94027
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Amrubicinhydrochloride(CAS DataBase Reference)
NIST Chemistry Reference: Amrubicinhydrochloride(92470-31-0)
EPA Substance Registry System: Amrubicinhydrochloride(92470-31-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 92470-31-0(Hazardous Substances Data)

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Usage
SDS
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92470-31-0 Usage

Uses

Used in Oncology:
Amrubicin hydrochloride is used as an anticancer agent for the treatment of various types of cancer, including small cell lung cancer and ovarian cancer. It is administered via intravenous infusion and works by inhibiting the growth of cancer cells and inducing apoptosis, making it a valuable option for patients who have not responded to other chemotherapy treatments.
Used in Second or Third Line Treatments:
Amrubicin hydrochloride is used as a second or third line treatment option for patients with cancer who have not responded to initial chemotherapy regimens. Its effectiveness in inhibiting cancer cell growth and inducing apoptosis makes it a valuable alternative for those who have exhausted other treatment options.
It is crucial to closely monitor patients receiving amrubicin hydrochloride for any signs of adverse reactions, such as bone marrow suppression, nausea, vomiting, and hair loss. Dosage adjustments may be necessary to ensure effective treatment while minimizing side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 92470-31-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,4,7 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 92470-31:
(7*9)+(6*2)+(5*4)+(4*7)+(3*0)+(2*3)+(1*1)=130
130 % 10 = 0
So 92470-31-0 is a valid CAS Registry Number.

92470-31-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name	5,12-Naphthacenedione, 9-acetyl-9-amino-7-[(2-deoxy-α-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-, hydrochloride, (7S-cis)-

1.2 Other means of identification

Product number	-
Other names	AMRUBICINHYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:92470-31-0 SDS

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