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(4S,5R,3'S)-4-methyl-5-phenyl-3-[3'-(2-methylbenzothiazol-5-yl)-3'-(tert-butyldimethylsilyloxy)-2'-oxopropyl]-2-oxazolidinone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

924727-16-2

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924727-16-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 924727-16-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,4,7,2 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 924727-16:
(8*9)+(7*2)+(6*4)+(5*7)+(4*2)+(3*7)+(2*1)+(1*6)=182
182 % 10 = 2
So 924727-16-2 is a valid CAS Registry Number.

924727-16-2Downstream Products

924727-16-2Relevant academic research and scientific papers

Total synthesis and antitumor activity of ZK-EPO: The first fully synthetic epothilone in clinical development

Klar, Ulrich,Buchmann, Bernd,Schwede, Wolfgang,Skuballa, Werner,Hoffmann, Jens,Lichtner, Rosemarie B.

, p. 7942 - 7948 (2007/10/03)

Going to trial: From about 350 active epothilone analogues synthesized by a highly convergent synthesis, one (ZK-EPO, see picture) has been chosen for clinical development on the basis of its outstanding preclinical data. This compound exhibits higher activity and efficacy than taxanes (e.g. paclitaxel) and second-generation epothilones, a fast and efficient cellular uptake, no recognition by efflux mechanisms, and an improved therapeutic window. (Chemical Equation Presented)

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