924884-28-6Relevant articles and documents
Benzyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate, a versatile intermediate for the synthesis of 3,3-dimethylproline derivatives
Medina, Jesus R.,Blackledge, Charles W.,Erhard, Karl F.,Axten, Jeffrey M.,Miller, William H.
, p. 3946 - 3949 (2008/09/19)
(Chemical Equation Presented) The synthesis of racemic nitrile (±)-9 was accomplished in four steps and 58% overall yield from the known pyrrolidinone 5. Nitrile (±)-9 was resolved via preparative chiral HPLC to afford optically pure nitriles (+)-9 and (-